Mechanism of digitalis action

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Magnesium's Mechanism of Action in Digitalis-induced Arrhythmias

The mechanism by which magnesium affects digitalis-induced arrhythmias was studied in dogs with and without beta-receptor blockade. Digoxin was infused at a rate of 2.5,ug/kg/min until ventricular tachycardia developed, then half the animals were given MgSO4, the other half saline. In animals given MgSO4, sinus rhythm was immediately re-established; in animals given saline, ventricular tachycar...

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Studies on magnesium's mechanism of action in digitalis-induced arrhythmias.

The mechanism by which magnesium affects digitalis-induced arrhythmias was studied in dogs with and without beta-receptor blockade. Digoxin was infused at a rate of 2.5mug/kg/min until ventricular tachycardia developed, then half the animals were given MgSO4, the other half saline. In animals given MgSO4, sinus rhythm was immediately re-established; in animals given saline, ventricular tachycar...

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The Action of Digitalis in Pneumonia

We have shown in a series of 105 cases of pneumonia, 95 of which we have selected as available for statistical study, that digitalis given by mouth has an action on the heart. We have judged this action to be present because changes occurred in the auriculoventricular conduction time and in the form of the T wave of the electrocardiogram, just as they do in the non-febrile heart. This conclusio...

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Ions and the action of digitalis.

Digitalis acts mainly on the heart. It affects excitability, conduction of impulses, and force of contraction. The physiology of all these processes has been elucidated greatly in the past 20 years, particularly by Hodgkin and Huxley and their collaborators. Techniques of inserting micro-electrodes into nerve and muscle cells have made possible both the recording of transmembrane potentials in ...

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Mechanism of Action of the Thyroid Hormone on the Heart

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ژورنال

عنوان ژورنال: Folia Pharmacologica Japonica

سال: 1961

ISSN: 0015-5691,1347-8397

DOI: 10.1254/fpj.57.66